As such, its IUPAC systematic name is methylbenzene. Toluene is predominantly used as an industrial feedstock and a solvent. As the solvent in some types of paint thinner, contact cement and model airplane glue, toluene is sometimes used as a recreational inhalant In 1841, French chemist Henri Étienne Sainte-Claire Deville isolated a hydrocarbon from balsam of Tolu (an aromatic extract from the tropical Colombian tree Myroxylon balsamum), which Deville recognized as similar to Walter's rétinnaphte and to benzene; hence he called the new hydrocarbon benzoène. Because the methyl group has greater electron-releasing properties than a hydrogen atom in the same position, toluene is more reactive than benzene toward electrophiles. It undergoes sulfonation to give p-toluenesulfonic acid, and chlorination by Cl to give ortho and para isomers of chlorotoluene. Importantly, the methyl side chain in toluene is susceptible to oxidation. 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Over half reported significant fatigue at 6 months and 20% at a year had not causes of fatigue need to be excluded, many other which, particularly an under active thyroid, can be easily treated. If you are in the process of weaning yourself off of tamoxifen (and there are many reasons why you might want to do so) and need help with the resulting withdrawal side effects, this article shares some tried and true natural remedies to help you out. There are many reasons for these side effects but the major one is that while tamoxifen initially acts as an estrogen-blocker, over time it begins to have estrogen-like activities. When a person has been on tamoxifen for a lengthy period (and that time period varies between people) they can begin to metabolize the drug as they would estrogen, so withdrawing from it can bring on quite a few menopausal symptoms. Dr Scott M Sedlacek, an oncologist with Colorado Breast Specialists in Denver stated back in 1998 that when a woman stops taking the drug, she can experience estrogen withdrawal. Dr Selacek stated “Perhaps the longer a woman takes tamoxifen, the more likely it will be metabolized as an estrogen and therefore stimulate some of these cancers to recur.” And that is just what we are finding – the very drug that is meant to protect us from breast cancer recurrence CAN also cause it. I can’t tell you how many women I have personally spoken with who have told me that they took tamoxifen for the recommended five years, only to have breast cancer come back later. Tamoxifen is toxic to the body, especially to the liver. Even the US Government website advises “Long term tamoxifen therapy has been associated with development of fatty liver, steatohepatitis, cirrhosis, and rare instances of clinically apparent acute liver injury.” California has a law called Proposition 65 that requires the state to publish and maintain a list of known carcinogens. Does tamoxifen cause tiredness Fatigue from Tamoxifen? Cancer Survivors Network, Brisdelle® paroxetine non-hormonal Diflucan rash pictures Cialis knee pain Need to buy lexapro Best Synthroid Levothyroxine price - $0.35 per pill. Synthroid Levothyroxine available are sold at Best-Price-Checker.com! This month at half price! How much does levothyroxine cost - Best-Price Tamoxifen Oral Route Side Effects - Mayo Clinic Fatigue and tiredness - Cancernet Topic Tamoxifen, fatigue and emotional side effects Topic Tamoxifen, fatigue and emotional side effects. It took me awhile to find a site which listed fatigue as a Tamoxifen side effect. This threw us for a loop, cause this is the first we had heard anything of this. Anyway we did a pet scan, and it showed the spot in my lung, and. metoprolol interaction The tamoxifen also causes fatigue, but not as bad as the chemo and radiation. I am off all meds now but can relate to the extreme fatigue. I sleep a lot. Exercise 40 minutes 3 to 4 times a week and eat a well balanced healthy diet. I am still so fatigued. Some men have had sexual problems when taking this medicine tamoxifen tablets. These include lowered interest in sex and not able to get an erection. Call your doctor right away if you have sexual problems when taking this medicine tamoxifen tablets. What are some other side effects of Tamoxifen Tablets? All drugs may cause side effects.