So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Ophthalmology guidelines for plaquenil Purifying chloroquine phospahte I have taken plaquenil for lupus off and on for two years one day I started having panic attacks I stopped caffeine alcohol etc. The only thing that helped was stopping the plaquenil after feeling better and some time I thought I’d try it again after a flare. Because previous studies have found strong connections between Plaquenil and decreased lupus flares, the amount of damage to the body, and the favorable impact on survival, the researchers deemed it to be unethical to conduct a double-blind, placebo study. Instead, the researchers used statistical models to create two groups based on the. Sunlight causes lupus flares and also increases the risk of skin cancer. People with lupus should avoid the sun whenever possible. If you need to be outdoors, wear sunscreen with an SPF of 85 or greater and be sure that your sunscreen contains Helioplex to protect you from both UV-A and UV-B rays. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Chances of having a lupus flare when stopping plaquenil How is plaquenil hydroxychloroquine used to treat lupus?, Plaquenil Hydroxychloroquine for Lupus - LupusCorner Plaquenil sun spots Does anyone know if you have to be weaned off Plaquenil? I've been on it for 15 years, for Lupus? Asked by Lupie523 Updated 27 September 2018 Topics plaquenil, lupus erythematosus, insomnia, sjogren's syndrome, systemic lupus erythematosus, vision Does anyone know if you have to be weaned off Plaquenil? I've been on.. Lupus and Cancer Johns Hopkins Lupus Center. Immune & Autoimmune - Lupus Flares While Taking Plaquenil. Here are some things that may reduce the risk of both the onset of lupus, in those who are at risk, and a flare-up. Hydroxychloroquine Plaquenil This is an antimalarial drug. It can help to. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. This action suppresses the normally overactive immune response in lupus patients which may explain one reason Plaquenil works so well for those suffering with lupus. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months.