This type of malaria medication consists of two different drugs, one called chloroquine phosphate and one called proguanil hydrochloride, that are taken as two separate tablets but are packaged together. The two drugs are taken in combination to be more effective against malaria and as a form of malaria treatment, by inhibiting the reproduction of the parasites responsible for causing malaria. Hydroxychloroquine and hearing loss Hydroxychloroquine 400 mg for rheumatoid arthritis Bad side effects of hydroxychloroquine In a double-blind equivalence trial, 1083 participants travelling to a malaria-endemic area were randomly assigned to two treatment groups atovaquone-proguanil plus placebos for chloroquine and proguanil, or chloroquine, proguanil, and placebo for atovaquone-proguanil. For prophylaxis only in areas with chloroquine-sensitive malaria-Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly same day each week while in malarious areas and for 4 weeks after leaving such areas. Usual Pediatric Dose for Malaria. Infants and children Less than 60 kg In The Travel and Tropical Medicine Manual Fifth Edition, 2017. Author recommendations For travelers to areas with known or potential chloroquine-resistent malaria with a predominance of Plasmodium falciparum or Plasmodium vivax, clinicians should prescribe any of the following malaria preventive drugs mefloquin, doxycycline, chloroquine-proguanil, or atovaquone-proguanil. In some countries, chloroquine proguanil medication requires a prescription, and in other places it is available without a prescription, but it is recommended to consult a doctor before taking any malaria medication. Both these drugs can have serious side effects, especially when taken together, including itching, skin rash, stomach pain, bloody stool, and hair loss. Chloroquine-proguanil malaria prophylaxis Malaria Information and Prophylaxis, by Country S - CDC, Chloroquine Dosage Guide with Precautions - Can you take plaquenil with lipitor Mefloquine, taken to prevent malaria may increase the risk of convulsions or fits when taken at the same time as chloroquine. Levothyroxine thyroid medicine. Medicines used to treat epilepsy, as chloroquine may reduce their effectiveness. Chloroquine & Proguanil Anti-Malarial Tablets. Chloroquine Plus Proguanil - an overview ScienceDirect.. Chloroquine and/or Proguanil - Fit for Travel. Question Some of my pregnant patients wish to travel to malaria-endemic regions. Are there medications that can be used safely during pregnancy for malaria prophylaxis? Answer Pregnant women should avoid travel to malaria-endemic areas if possible. However, if travel cannot be avoided, measures to prevent mosquito bites, along with an effective. Chloroquine and Proguanil Malaria Prophylaxis Liverpool School of Tropical Medicine CHLOROQUINE Adult dose is 2 tablets taken once weekly. Other name Avloclor 155mg base. Child dosage of Chloroquine is according to weight. Chloroquine is available in a liquid form from a Jun 15, 2004 Major exclusion criteria included pregnancy and/or lactation, travel to an area where prophylaxis with chloroquine-proguanil would be inappropriate, a history of active malarial infection within 12 months of screening, and travel to an area where malaria is endemic within 60 days of screening. Design and procedures.