Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine alopecia Concordia plaquenil Take it once weekly while in the area, and continue taking it for 4 to 8 weeks after leaving the area or as directed by your doctor. To treat malaria, follow your doctor's lupus or rheumatoid arthritis, take this medication by mouth, usually once or twice daily or as directed. Your doctor may gradually increase your dose. I don't know for sure if it is the plaquenil or other meds but my rheumy seems to have my inflammation/stiffness under pretty good control. Been taking plaquenil and arava for about a year. Just rediced plaquenil from one tablet twice a day to one tablet once a day. I also take Cimzia injections bi-weekly but that has only been for about 6 months. Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. Check the latest outcomes from 53,829 Plaquenil users, or browse all drugs. What is Inflammation? Inflammation has been reported by people with rheumatoid arthritis, high blood pressure, pain, osteoporosis, crohn's disease. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Will plaquenil take joint swelling away Plaquenil - Uses, Side Effects, Interactions., PLAQUENIL" Rheumatoid Arthritis Community - Support Group Allergy to plaquenil after being on it for yearsChloroquine inhibits autophagic flux by decreasing autophagosome lysosome fusionHydroxychloroquine and t cellsHydroxychloroquine organ damage A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. How effective is Plaquenil for Inflammation by duration.. What next if plaquenil doesn't work? -. Sep 13, 2019 provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness. One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur.