Malaria resistance to chloroquine

Discussion in 'Pharmacy Northwest Canada' started by sergey_k, 06-Mar-2020.

  1. 100ru New Member

    Malaria resistance to chloroquine


    Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    To prevent malaria, take chloroquine once weekly on the same day each week, or as directed by your doctor. Start this medication usually 1 to 2 weeks before you enter the malarious area, continue. Chloroquine-resistant malaria is exactly what it sounds like—particular types of malaria which are not cured by treatment with chloroquine. Chloroquine was first discovered in the 1930s in Germany and began to be widely used as an anti-malaria post-World War II, in the late 1940s. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication.

    Chloroquine is also used to treat amebiasis (infection caused by amoebae). Chloroquine is used to treat and to prevent malaria.

    Malaria resistance to chloroquine

    Malaria understanding drug resistance - BugBitten, Chloroquine Resistant Malaria

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  5. Data suggest that the earthquake and ensuing hurricane and floods created the necessary conditions—inadequate shelters, population movement, and still water—to increase the incidence of malaria and possibly spread the recently identified chloroquine-resistant strains of P. falciparum. In France and Canada, laboratory surveillance for malaria found that 2 travelers from Haiti carried chloroquine-resistant strains.

    • Chloroquine-Resistant Malaria in Travelers Returning from..
    • Chloroquine - Wikipedia.
    • CDC - Malaria - Travelers - Malaria Information and..

    Plasmodium falciparum chloroquine resistance is a major cause of worldwide increases in malaria mortality and morbidity. Recent laboratory and clinical studies have associated chloroquine resistance with point mutations in the gene pfcrt. Chloroquine, an old malaria drug, may help treat novel coronavirus, doctors say Chloroquine, or hydroxychloroquine, has been used to treat malaria since 1944. The development of chloroquine resistance by malaria parasites is increasing at an alarming rate especially in the tropical countries where it is used extensively as an antimalarial drug 2. In the past years, the drug of choice has changed from chloroquine to artemisinin.

     
  6. Anton_S Guest

    In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk. Hydroxychloroquine - Safe In Breastfeeding Plaquenil Warnings and Precautions Fluconazole Oral Route Before Using - Mayo Clinic
     
  7. er670 Guest

    This is not a list of all drugs or health problems that interact with chloroquine. Chloroquine - Wikipedia Chloroquine C18H26ClN3 - PubChem Clinical Pharmacokinetics and Metabolism of Chloroquine.
     
  8. NATATRX New Member

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