Hydroxychloroquine weight based dosing 5 mg kg ideal bo

Discussion in 'Online Pharmacies Of Canada' started by rengen, 12-Mar-2020.

  1. DocS Well-Known Member

    Hydroxychloroquine weight based dosing 5 mg kg ideal bo


    Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid).

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    There is an increased risk of HCQ retinopathy with increase in the cumulative dose. Per the prior 2011 AAO guidelines the recommended maximum dose to minimize HCQ retinal toxicity was 6.5 mg /kg based on ideal body weight 2. The advantage of the real body weight formula is that it distributes the risk evenly on a broad range of body habitus. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. The dosage is based on body weight. 6.5 mg/kg. Excess Hydroxychloroquine Dosing All Too Common. 54.3 percent of patients who started HCQ before the 2011 recommendations were exceeding the 2011 dosing threshold of 6.5 mg/kg/day per ideal body weight, compared with 49.4 percent who started HCQ therapy after the 2011 guidance. the authors note that the likelihood of a “safe” dose of.

    It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015.

    Hydroxychloroquine weight based dosing 5 mg kg ideal bo

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  3. We consider this supportive of dosing based on actual body weight 6.5 mg per kg with a cap at 400 mg per day. From a practical perspective, this means the daily dose should be reduced, from 400 mg per day, for those weighing less than 61 kg 134lbs. Hydroxychloroquine Blood Levels and Adherence

    • The Role of Hydroxychloroquine Blood Levels in SLE RheumNow..
    • Excess Hydroxychloroquine Dosing All Too Common.
    • Measuring hydroxychloroquine blood levels could inform safe, optimal dosing.

    However, since Mackenzie’s time, there have now been multiple reported cases of hydroxychloroquine retinopathy in patients who developed retinopathy despite taking less than 6.5 mg/kg/d based on IBW, not ABW.4,27,30,31,33 Therefore, 6.5 mg/kg/d based on IBW has been transformed from the threshold for safe dosing to the threshold for toxic dosing. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. NEW DOSE RECOMMENDATIONS FOR PLAQUENIL HYDROXYCHLOROQUINE USAGE IN TREATING # lupus? # ACR14 SHARE with everyone taking Plaquenil! Sorry no recent posts. a week of vacation. but now I am at the annual American College of Rheumatology ACR meeting where the latest in lupus research is being presented.

     
  4. lagalla User

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Plaquenil for UCTD - Autoimmune diseases - Inspire Plaquenil UCTD - General Discussion - Life With Lupus Hydroxychloroquine - Plaquenil Alternative - LUPUS UK
     
  5. pechene Guest

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  6. busy New Member

    How can I control the purple bruising on my skin from Warfarin? Jul 21, 2010 I have been taking warfarin for many years. It seems to agree with me and my INR is normal most of the time but my question is "How do control my skin from turning purple with the slightest movements. I used to just bruise but I now have massive dark purple bruise looking patches under my skin.

    Has anyone taking Plaquenil ever experienced bruising under.