Hydroxychloroquine and trametinib

Discussion in 'Northwest Pharmacy Canada' started by Edantses, 28-Feb-2020.

  1. hochongs Moderator

    Hydroxychloroquine and trametinib


    Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    Jan 31, 2019 Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer THREAD The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government. Finally, treatment of a patient with PDA with the combination of trametinib plus hydroxychloroquine resulted in a partial, but nonetheless striking disease response. These data suggest that this. This phase I trial studies the sides effects and best dose of hydroxychloroquine when given together with trametinib in treating patients with pancreatic cancer that has spread to nearby tissue, lymph nodes or other places in the body and cannot be removed by surgery. Trametinib may stop the growth.

    Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria.

    Hydroxychloroquine and trametinib

    Dabrafenib, Trametinib and Hydroxychloroquine in Patients With Advanced., Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a.

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  6. A Phase I clinical trial to study the side effects and best dose of hydroxychloroquine when given together with trametinib in treating patients with pancreatic cancer.

    • Phase I Study of Trametinib and Hydroxychloroquine in Treating Patients..
    • Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic..
    • Trametinib and Hydroxychloroquine in Treating Patients..

    Phase I Trial of Trametinib and Hydroxychloroquine in Patients With Advanced Pancreatic Cancer THREAD Summary The purpose of this phase I trial is to study the side effects and best dose of hydroxychloroquine when given together with trametinib in treating patients with pancreatic cancer that has spread to nearby tissue, lymph nodes or other places in the body and cannot be removed by surgery. Fig. 4 Treatment of a pancreatic cancer patient with trametinib plus hydroxychloroquine T/HCQ led to a reduction in tumor marker cancer antigen 19-9 CA19-9 and overall tumor burden. The primary purpose of this study is to determine the maximum tolerated dose MTD and preliminary safety of hydroxychloroquine HCQ when administered in conjunction with oral dabrafenib and trametinib D+T in patients with advanced BRAF mutant melanoma.

     
  7. tanin Moderator

    Treatment for multiple myeloma can often help to control symptoms and improve quality of life. This means additional treatment is needed when the cancer comes back (a relapse). Types of Cancer Linked to Rheumatoid Arthritis Multiple Myeloma Treatment Options DARZALEX® daratumumab What Conditions does Plaquenil Treat? - WebMD
     
  8. killgur Moderator

    Plaquenil Uses, Dosage & Side Effects - Apr 10, 2019 Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye.

    Hydroxychloroquine Side Effects, Dosage, Uses, and More