These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Plaquenil and ssri Is hydroxychloroquine an opioid Ra hydroxychloroquine Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. Summary Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Stopping plaquenil effects Hydroxychloroquine Side Effects, Dosage, Uses, and More, Will you have Withdrawal syndrome with Plaquenil - eHealthMe Plaquenil for pain controlHydroxychloroquine 300 mgChloroquine indications Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Rx Side Effects New Plaquenil Guidelines and More.. Side effects to Stopping Plaquenil. - Sarcoidosis - Inspire. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Hi honey, YES.stopping plaquenil for a couple of days can cause symptoms to arise or get worse.needs to be taken exactly as prescribed. Twice a day, every day. Missing one dose wont make a major difference but skipping more then one, or days absolutely can.