Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Chloroquine is used for Chloroquine cell signalling Pregnancy category hydroxychloroquine Plaquenil comes in tablet form. It is taken once or twice a day, unless it is used for the prevention of malaria, in which case it is taken once a week beginning 1 to 2 weeks prior to traveling to an area where malaria is common. Take this medication with a meal or a glass of milk to prevent stomach upset. Drug interactions are reported among people who take Plaquenil and Milk thistle together. This study is created by eHealthMe based on reports of 25 people who take Plaquenil and Milk thistle from Food and Drug Administration FDA, and is updated regularly. eHealthMe is the source of postmarketing drug monitoring. For lupus erythematosus, one or two tablets are usually taken once or twice daily. For rheumatoid arthritis, one to three tablets are usually taken once a day. Hydroxychloroquine can be taken with a glass of milk or a meal to decrease nausea. Follow the directions on your prescription label carefully. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Can you take plaquenil with milk Plaquenil Indications, Side Effects, Warnings -, Plaquenil and Milk thistle drug interactions - eHealthMe Is hydroxychloroquine safe in pregnancy Plaquenil passes through breast milk. Therefore, if you are breastfeeding or plan to start, be sure to talk with your healthcare provider about using Plaquenil see Plaquenil and Breastfeeding for more information. Plaquenil Warnings and Precautions. Hydroxychloroquine MedlinePlus Drug Information. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. If you miss a dose, take it as soon as you remember. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug.