Chloroquine in amoebic liver abscess

Discussion in 'Hydroxychloroquine 200 Mg Tablet' started by Alexdov, 21-Feb-2020.

  1. Lele17 Moderator

    Chloroquine in amoebic liver abscess

    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    A patient with amebic abscess of the liver was treated with standard doses of metronidazole but remained febrile and pulmonary complications developed. Only after other forms of treatment including aspiration and administration of chloroquine phosphate and emetine hydrochloride did he begin to improve and ultimately to recover. Although amoebic liver abscess is infrequent in children, the outcomeis muchless favourable than it is in adults. When treated with combined emetinehydrochloride, chloroquine, andaspiration, the prognosis is excellent in adults Wilmot, 1962, this regime being more successful than treatment with a single drug Wilmot, Powell, and Adams, In 1948 Conan 1 reported 6 cases of hepatic amebiasis without abscess of the liver successfully treated with chloroquine. In the same year Murgatroyd and Kent 2 reported the cure of a case of refractory amebic abscess of the liver treated with chloroquine. The success of this treatment, after the failure of emetine, diiodo-hydroxyquinoline diodoquine® and penicillin given systemically and proflavine sulfate used locally, was striking.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine in amoebic liver abscess

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  3. Emetine hydrochloride and chloroquine in the treatment of children with amoebic liver abscess.

    • Emetine hydrochloride and chloroquine in the treatment of..

    Highly effective in the treatment of amebic liver abscess when administered with emetine or dehydroemetine. Like emetine and dehydroemetine, it is not effective against luminal forms. Irreversible retinal damage does not occur with the dose and duration used for the treatment of hepatic amebiasis. Nyu Liver Doctor – Treatment Chloroquine Abscess Amoebic because liver enlargement could be due to an infection such as Hepatitis it’s important to recognize and address fever when it occurs. I have been on milk thistle for about ultrasound etc. FDA Acetaminophen Damages Liver. Chloroquine in the Treatment of Amoebic Liver Abscess. HARINASUTA C. Chloroquine in the treatment of amoebic liver abscess. Ind Med Gaz. 1950 Feb; 85 237–41.

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    Authors: Dr Anes Yang, Clinical Researcher, Department of Dermatology, St George Hospital, University of New South Wales, Sydney, NSW, Australia; Dr Monisha Gupta, Senior Staff Specialist, Department of Dermatology, Liverpool Hospital, Sydney, NSW, Australia. It is a hydroxylated version of chloroquine, with a similar mechanism of action. Normocomplementaemic urticarial vasculitis effective. New use for an old treatment Hydroxychloroquine as a. REFERENCES - UpToDate
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