I'm just wondering if actually the hydroxychloroquine could be the explanation. Initially I had a bit of an upset stomach but this seemed to pass. Just wondering if anyone out there has developed nausea/sickness after being on it for some time? Difference between hydroxychloroquine Plaquenil and mosquito bites Oct 24, 2009 Methotrexate is a wonderful drug for Rheumatoid arthritis. However, the nausea associated with the same can be quite a disturbing problem. At times, it is so severe that one has to discontinue methotrexate despite the relief provided by it. Can you overcome the nausea related to Methotrexate? Yes! here are a few tips— Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Nausea, stomach cramps, loss of. Nausea and vomiting, loss of appetite, and abdominal pain are some of the possible side effects of Plaquenil. In most cases, side effects of this medication are usually minor and do not require medical attention. I take 1 in the morning with food & 1 before I go to bed. Thanks for reading this Mary Hi Mary, I've been on it now for almost 3 years. Plaquenil nausea vomiting Lupus Nausea" Lupus Community - Support Group, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil versus hydroxychloroquine Sep 13, 2019 Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Hydroxychloroquine Side Effects Common, Severe, Long Term.. Plaquenil Side Effects - eMedTV Health Information.. Can Plaquenil cause acid reflux and pain when swallowing?. Feb 19, 2020 Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation. No more stomach issues, nausea, vomiting, joint pains, and rash. It was a night and day difference. So bottom line generic hydroxychloroquine gets a 0/5 rating from me and the brand name. Hi guys, I'm on plaquenil since December 2 times a day 200 MG and since then I experience nausea on a daily base. Is there someone with a similar experience and maybe the golden tip? If the nausea doesn't disappear within the next month I'm going to consult my rheumatologist. Thank you.