So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Eye doctors for plaquenil screening Hydroxychloroquine lupus nephritis Can i take plaquenil at the same time as metformin Early oct changes plaquenil How does it differ from lupus in severity, and does it advance on the same timetable as lupus? Howard_Smith,_MD Lupus and Sjogren’s syndrome are both autoimmune diseases, that is, the body is attacking itself. They are distinct, separate diseases; however, many patients have both of them at the same time. It's hard to generalize about severity. After just 4 days on Plaquenil, I had severe stomach cramps, no appetite, GERD pain, diarrhea and a migraine. Not sure that the migraine was related but it happened on day 4. After contacting my Rheumatologist, I was told to stop taking the drug. When I asked what other drug I could try. The first symptoms of lupus usually occur somewhere between the teen years and the 30s and may be mild, severe, sporadic, or continual. Common general symptoms include fatigue, fever, and hair loss. Lupus can also affect individual organs and body parts, such as the skin, kidneys, and joints. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Does plaquenil stop progression of lupus Plaquenil. A medication for Lupus, Stomach cramps from Plaquenil - what to do? Lupus Forums. Can you take plaquenil if you are allergic to sulfateReactions to plaquenil Basically, plaquenil's effect is to modulate the immune system, which is something that could be quite beneficial for some of us. You can do what you want, but you might want to consider giving plaquenil more of a chance, and be far more wary of the prednisolone prednisone/steroid. Plaquenil pros and cons - Sclero Forums MAIN - Sclero Forums. Lupus Disease Information Johns Hopkins Lupus Center. Immune & Autoimmune - Lupus Flares While Taking Plaquenil. Plaquenil does help with some of the symptoms of Lupus, but it does take a few weeks to start helping. It's most important role is to inhibit progression of the disease -- I'm really surprised you haven't been on it ever since the Lupus was diagnosed. Anti-Malarial drugs. An anti-malarial drug controls lupus in some patients long-term. This requires the patient to be on these drugs for the rest of their lives, and an example is Plaquenil. Side effects associated with the drugs include loss of appetite, retinal damage, dry skin, stomach upset and bloating. After 1 1/2 yrs of my Rheumatologist after me to take the Plaquenil, I'm finally doing it. I have an eye doctors appointment this week and I'll take my first pill after the check up. I am so very scared of it. Thanks to luppylupus Thank you for explaining what the Plaquenil does and how it does it.