According to my rheumatologist, plaquenil is good at clearing up skin involvement. I have ring shaped and oval shaped lesions that have healed but you can still see them if i remove my makeup. I am dying to talk to someone who has Cutaneous lupus. I did not know that cutaneous can turn into discoid lesions. My only symptoms are that my hands turn dark red from the flurouscent lights at work and the sun, I lose hair, and the 4-6 wk flare up on my face which left a quarter shape on my chin, cheeks and corner of cheeks. I haven't gotten any outbreaks on my body except a skin rash (very small). My knuckles, fingers, and once my complete hand turned dark red and then purple. Hey Angelina, UCTD stands for "undifferentiated connective tissue disease," which means I have some sort of autoimmune connective tissue disease (like, lupus, RA, polymyositis, scleroderma are all named, differentiated connective tissue diseases) but it doesn't fit the definition of any of the named diseases. i asked my doctor if he ever heard of this and he said yes. A few months into taking plaquenil, I'm barely getting any more skin lesions. I was diagnosed with Subacute cutaneous and have read that I can get discoid lesions from cutaneous. I have ring shaped and oval shaped lesions that have healed but you can still see them if i remove my makeup. I am dying to talk to someone who has Cutaneous lupus. For mold in your body heavy metals chloroquine Plaquenil for gout Chloroquine glioblastoma Plaquenil wonder drug Discoid lupus erythematosus and subacute cutaneous lupus erythematosus For use if response to local therapy is inadequate or impractical due to widespread skin lesions Clarke 2019; Kuhn 2017 Oral 200 to 400 mg daily as a single daily dose or in 2 divided doses. Note Due to the risk of retinal toxicity. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Cutaneous lupus erythematosus CLE is the second most common presenting symptom of autoimmune lupus erythematosus LE. Lesions precede the onset of systemic symptoms in 25 percent of patients, many of whom present to dermatologists for their initial evaluation.1 Prompt diagnosis of CLE requires a thorough understanding of the cutaneous manifestations and clinical spectrum of lupus. OR does it just help with Systemic Lupus - the organs? My dermatologist said it will probably happen again. My hands turn dark red and my palms and then it goes away. emedicine.medscape.com/article/1065657-overview It looks like staying out of the heat and sun (including florescent and halogen lights) might benefit you. This happens daily from anywhere from 5 minutes to 20 minutes or so. Does anyone else have this and does anyone else have cutaneous lupus and does plaquenil get the "wild fire' eruptions on the face to stop or slow down??? Best of luck, I take plaquenil for my UCTD, which manifested as muscle pain and skin lesions on my torso and legs. I was diagnosed with Subacute cutaneous and have read that I can get discoid lesions from cutaneous. Plaquenil for subacute cutaneous lupus Effects of Hydroxychloroquine in Patients With Cutaneous., Treating Lupus with Anti-Malarial Drugs Johns Hopkins. How long for hydroxychloroquine to leave the bodyFolic acid and hydroxychloroquine dosingPlaquenil and liver enzymesChloroquine phosphate reef2reef My UCTD includes skin lesions that, on biopsy, look like lupus lesions. So, I don't have subacute cutaneous lupus, but I do have lupus-like skin involvement that resolved pretty well with Plaquenil. I am sorry you're dealing with this-- skin involvement is really frustrating, I know! CUTANEOUS SUBACUTE LUPUS -. Treatment of Cutaneous Lupus Erythematosus. Cutaneous Lupus Erythematosus Dermatology JAMA Dermatology JAMA.. Subacute cutaneous lupus erythematosus SCLE. This can cause two kinds of lesions red, ring-shaped sores that sometimes overlap like interlocking circles, and a raised rash that resembles psoriasis. Some people have both. SCLE can occur anywhere on your body except your face, and like other types of cutaneous lupus, is often triggered by sunlight. Today’s AMs are hydroxychloroquine Plaquenil®, chloroquine Aralen®, and quinacrine Atabrine®. Quinacrine is no longer marketed in the U. S.; it can be dispensed by a compounding pharmacy, although insurance companies may not pay for it. The antimalarial quinine was first used to treat cutaneous lupus in 1834. Hydroxychloroquine is the drug of choice for systemic therapy of subacute cutaneous lupus erythematosus SCLE. Chloroquine is second line. The lowest possible dose needed to control the patient’s disease should be used.