Primaquine kills the liver stages, known as hypnozoites, of these forms of malaria, preventing relapse of infection later on. However, primaquine is known to cause severe haemolytic anaemia in people who are G6PD deficient. Hydroxychloroquine plaquenil drug class Hydroxychloroquine blurred vision due to Plaquenil cdc Chloroquine epilepsy A reduction in the amount of functional glucose-6-phosphate dehydrogenase appears to make it more difficult for this parasite to invade red blood cells. G6PD deficiency glucose-6-phosphate dehydrogenase deficiency occurs most frequently in areas of the world where malaria is common. Drug names in RED are of high risk to all deficiency variants. Names in GREEN are of low risk. Only 4% of patients were G6PD deficient, all of which were African American. Overall, there were no incidents of hemolysis reported in over 700 months of HCQ exposure among the 11 G6PD-deficient patients. Two G6PD-deficient patients experienced hemolysis during severe lupus flares that occurred while not taking HCQ. Patients with severe G6PD deficiency should not take primaquine; unfortunately at this stage there are no alternative drug regimens available. G6PD deficiency is restricted to certain populations or segments of populations; therefore it may be that not every person requiring primaquine will be tested for their G6PD status, only those considered high risk for potential deficiency. Is chloroquine safe for g6pd deficiency Glucose-6-phosphate Dehydrogenase Deficiency. G6PD Patient, Drugs Official List - Chloroquine pharmacokineticsWhat is in hydroxychloroquineFolic acid and plaquenil G6PD Deficiency / Safe & Unsafe / Drugs Official List; List of All Drugs Search drug groups, ingredients and trade names ACCESS LIMITED TO MEDICAL PERSONNEL AND PAYING MEMBERS Drug names in RED are of high risk to all deficiency variants. Names in GREEN are of low risk. Drugs Official List - G6PD Deficiency Association. Is Hydroxychloroquine Safe for Patients with G6PD Deficiency?. G6PD and Malaria –. Education and information regarding choosing a drug to prevent malaria, including a list of all available drugs and reasons for taking or not taking a certain drug. Chloroquine Adults 300 mg base 500 mg salt, once/week. G6PD deficiency; Cannot be used in patients who have not been tested for G6PD deficiency; Primaquine should not be prescribed for patients with severe G6PD deficiency see CONTRAINDICATIONS. In case of mild to moderate G6PD deficiency, a decision to prescribe Primaquine must be based on an assessment of the risks and benefits of using Primaquine. Who should not take Chloroquine Phosphate. anemia from pyruvate kinase and G6PD deficiencies; Allergies. nor should it be construed to indicate that use of a particular drug is safe.