Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Renault's disease hydroxychloroquine Plaquenil halps discoid lupus Imuran plaquenil together headache Dec 04, 2014 This baseline evaluation entails a dilated fundus examination, 10-2 white pattern visual field test subjective, and at least one of the following objective tests Spectral-domain optical coherence tomography SD-OCT, fundus autofluorescence FAF, or multifocal electroretinogram mfERG. Ivocal signs of chloroquine maculopathy bilateral peri-central scotoma in the visual fields, structural alterations of the macula in the optical coherence tomography but normal or atypical findings as to fundus autofluorescence imaging. Results In all patients, optical coherence tomography showed perifoveal thinning and subtle alterations of the outer retinal layers. In one patient, the. Apr 19, 2011 Specifically, spectral domain OCT is one of three objective tests now recommended for routine screening of patients on Plaquenil. The other two are multifocal electroretinogram mfERG and fundus autofluorescence FAF. Why the change in the recommendations? Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Fundus autofluorescence plaquenil The Nuts and Bolts of Fundus Autofluorescence Imaging., FUNDUS AUTOFLUORESCENCE FINDINGS IN EARLY CHLOROQUINE. Is there withdrawal from hydroxychloroquine At right, FAF image shows large soft drusen associated with increased fundus autofluorescence in a patchy FAF pattern. There are also more defined areas of hyper-AF corresponding to mixed drusen in a focal increased pattern superior and inferior to the fovea. A Clinical Guide to Fundus Autofluorescence. Don’t Drop Patients on Plaquenil - Review of Optometry. Unusual Fundus Autofluorescence Appearance in a Patient with.. Hydroxychloroquine Plaquenil is a chloroquine derivative used in the treatment of many diseases including malaria, rheumatoid arthritis, and systemic lupus erythematosus. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Fundus Autofluorescence FAF. Plaquenil Hydrochloroquine or Aralen Chloroquine • Annual screening after 5 years of use **Interesting, The Royal College of Ophthalmologists in Great Britain does NOT recommend routine screening for toxicity with antimalarial drug use. Fundus autofluorescence, or FAF is an imaging technique utilized to aid in the documentation and monitorization of retina health and function. The retina is the neurosensory layer of the eye that transmits the optical images we see into the electrical images our brain understands.