What is the process of making chloroquine

Discussion in 'Chloroquine 150 Mg' started by Sellovich, 22-Feb-2020.

  1. ritrgjdfvf User

    What is the process of making chloroquine


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    Chloroquine, 7-chloro-4-4-diethylamino-1-methylbutylamino-quinoline 37.1.3, is made by reacting 4,7-dichloroquinoline 37.1.1.1 with 4-diethylamino-1-methylbutylamine 37.1.1.2 at 180 °C 1–3. In order to realize the synthesis, the necessary 4,7-dichloroquinoline 37.1.1.1 is prepared in several ways from 3-chloroaniline. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. Chloroquine blocks the virus's ability to acidify endosomes and release its RNA into the cell, which is a critical step for most viruses to begin their infection.

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    What is the process of making chloroquine

    Chemical Reactions That Occur During Baking Sciencing, Chloroquine - Wikipedia

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  7. Chloroquine phosphate is in a class of drugs called antimalarials and amebicides. It is used to prevent and treat malaria. It is.

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    Objective To develop and validate a simple procedure for the qualitative determination of chloroquine in urine with potential for use in developing countries lacking sophisticated analytical equipment and expensive reagents. Sep 15, 2009 Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain Daniel P. Iwaniuk, 1 Eric D. Whetmore, 1 Nicholas Rosa, 1 Kekeli Ekoue-Kovi, 1 John Alumasa, 1 Angel C. de Dios, 1, 3 Paul D. Roepe, 1, 2, 3 and Christian Wolf 1, 3 Chloroquine is used to prevent and treat malaria. It is also used to treat liver infection caused by protozoa extraintestinal amebiasis. Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito.

     
  8. Maksim Well-Known Member

    Plaquenil tablets contain the active ingredient hydroxychloroquine, which is a type of medicine called a disease-modifying anti-rheumatic drug (DMARD). Rabies Vaccines Plaquenil - Side Effects, Uses, Dosage, Overdose. Vaccinations and Rheumatoid Arthritis
     
  9. GTHack Moderator

    Drug spotlight on hydroxychloroquine Lupus Foundation of. Individuals beginning HCQ therapy should be informed of the possibility, although extremely rare, of retinal toxicity, and told that periodic monitoring can lead to early recognition of some symptoms. Hydroxychloroquine is the most commonly used AM, specifically because it has a lower risk for retinal toxicity than chloroquine.

    Plaquenil Hydroxychloroquine - Side Effects, Dosage.