One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine vs hydroxychloroquine Plaquenil slecht zien Tell me about plaquenil Plaquenil safe to take Aug 25, 2019 Hydroxychloroquine and Chloroquine have a similar dose related risk assessment. 10mg / kg is potentially toxic. Increasing mortality is expected at doses 30mg / kg. 5 grams in adults is fatal without intervention. Children Ingestion of just one tablet can be fatal in the under 6 year. Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. Chloroquine phosphate tablets should not be used in these conditions unless the benefit to the patient outweighs the potential risks. Usage in Pregnancy Usage of Chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Chloroquine poisoning Chloroquine C18H26ClN3 - PubChem, Chloroquine and Hydroxychloroquine Toxicity Practice. How can plaquenil affect your eyesIncreased gas plaquenilHydroxychloroquine contraindications This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Hydroxychloroquine-Induced Retinal Toxicity - American.. Chloroquine - FDA prescribing information, side effects and uses. Chloroquine - Wikipedia. Hours ago The Lagos State government on Friday disclosed that following the announcement by President Donald Trump on Thursday that chloroquine can cure coronavirus, hospitals in the state has received patients suffering from chloroquine poisoning. The Lagos State government, through the Senior Special Assistant SSA on Health, Dr. Oreoluwa Finnih was quoted by the Chief Press Secretary to the governor, Mr Gboyega Akosile, as saying that some hospitals in the state are now treating patients who took too many quantities of chloroquine, leading to poisoning. Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ.