Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. Plaquenil company Chloroquine breast cancer How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. My question is for those that have taken Plaquenil/Hydroxychloroquine. How long did it take for it to remove symptoms in your personal experience? I know I've read it can take up to 6 months but what I'm wondering is, do you just wake up one day and find it's kicked in 6 months down the road or more likely, it starts to work slowly over 6 months? Nov 25, 2013 Hi Tatavero there are a few reasons that it may take longer to get out of your system like if it was take with food or if you have certin medical conditions but with most people to completly clear your body the regular 1/2 life of the drug is 7 to 15 hours so in the longest clearing would be about 23 to 30 hours to be completley out which most passes through your urine. good luck and have a great holiday season. Please check with the appropriate physician regarding health questions and concerns. The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Hydroxychloroquine how long does it stay in body Plaquenil Oral Uses, Side Effects, Interactions, Pictures., How long did Plaquenil/Hydroxychloroquine take. Plaquenil et psoriasisPlaquenil side effects Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks. Hydroxychloroquine MedlinePlus Drug Information. Hydrochlorothiazide - how long does it take to eliminate in.. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. On average it would take over 8 months for all the hydroxychloroquine to be gone from a person’s body. Some women may choose to stop taking this medication before becoming pregnant; however, it’s important not to stop any medications before talking with a health care provider. If you are taking hydroxychloroquine over a long duration, it is important to take eye exams every 6 to 12 months. 6 Do not take hydroxychloroquine if you experience vision symptoms, including problems seeing or reading, light sensitivity, blurred distance vision, or light flashes or streaks. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. To treat malaria Hydroxychloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take this medicine for the full prescribed length of time for malaria.