It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Can plaquenil cause eye dryness Chloroquine injection intravenous Why does hydroxychloroquine cost so much Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Jun 01, 2018 Plaquenil is an immunomodulatory drug DMARD that works by suppressing the immune system to prevent it from damaging tissues and joints. The immune system helps protect the body from harmful substances such as infectious agents and bacteria. Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation when an infection is found, and these basically malfunction with inflammatory disorders. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Does plaquenil lower your immune system Plaquenil and immune system Lupus Forums at The Lupus Site, Plaquenil Moa of plaquenil Oct 15, 2012 The way it was explained to me is that Plaquenil is not an immunosuppresant, but is used because of its anti-inflammatory effect, so it alone should not lower your ability to fight infections. Plaquenil and lowered immune system - Sjogren's World. Inflammatory Osteoarthritis And Plaquenil. Reasonably Well Plaquenil FAQ. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory pathways. Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. My rheumy has saidand everything I've read on Plaquenil that Plaquenil NEEDS that amount of time to build in your system before it stats to have beneficial effects. Feb 04, 2015 plaquenil, medicine, chronic, drug. For three months I have cold after cold with chronic and sometimes violent coughing. I have been given many medicines to fight the viruses with little success. I never had this much trouble before taking plaquenil. I was diagnosed with Lupus in April of 2014.