Chloroquine induced cardiomyopathy

Discussion in 'Canada Pharmaceuticals Online' started by Kandrat, 12-Mar-2020.

  1. YulianSh Guest

    Chloroquine induced cardiomyopathy


    Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention.

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    A 61-year-old woman with a 30-year history of systemic lupus erythematosus treated with chloroquine sulfate presented with complete heart block, congestive heart failure, and findings of restrictive cardiomyopathy on echocardiogram. Hydroxychloroquine is used in the treatment of various rheumatic conditions including systemic lupus erythematous. Hydroxychloroquine induced myopathy is rare adverse reaction but symptoms are usually recover after discontinuation of the drug. Electron microscopy of the myocytes demonstrated dense, myeloid, and curvilinear bodies. The diagnosis of hydroxychloroquine-induced cardiomyopathy was made based on the clinical, hemodynamic, and pathologic findings. This is the first case report describing chloroquine-induced cardiomyopathy involving the heart conduction system.

    Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine.

    Chloroquine induced cardiomyopathy

    Hydroxychloroquine-induced cardiomyopathy and heart., A Rare but Reversible Cause of Myopathy Hydroxychloroquine Induced.

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  5. Chloroquine CQ and hydroxychloroquine HCQ are anti‐rheumatic medications frequently used in the treatment of connective tissue disorders. We present the case of a 45‐year‐old woman with CQ‐induced cardiomyopathy leading to severe heart failure.

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    A myocardial biopsy was performed with the diagnosis of chloroquine induced cardiomyopathy. Histology H&E staining in Figure A shows extensive cytoplasmic vacuolization, along with areas of extensive myocyte degeneration and severe disarray of myofibrils. There is marked nuclear dysmorphism, and many nuclei are small and hyperchromatic. Drug-induced heart and vascular disease remains an important health burden. Hydroxychloroquine and its predecessor chloroquine are medications commonly used in the treatment of systemic lupus erythematosus, rheumatoid arthritis, and other connective tissue disorders. To the Editor Chloroquine CQ has been used for the treatment and prophylaxis of malaria since World War II. Ten years later, the administration of CQ and hydroxychloroquine HCQ was introduced for the longterm therapy of rheumatic diseases. Although no reliable statistical data are available, HCQ, which differs from CQ only in a hydroxyl group at the end of the side chain, but not in.

     
  6. after7days XenForo Moderator

    Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). Hydroxychloroquine Side-effects, uses, time to work Hydroxychloroquine User Reviews for Systemic Lupus. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  7. bruner Guest

    Hydroxychloroquine Side Effects, Dosage, Uses, and More Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. If you develop these symptoms, call 911 or go to.

    Hydroxychloroquine toxicity - EyeWiki