They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. A patient will begin taking hydroxychloroquine for rheumatoid arthritisi Is plaquenil used for rheumatoid arthritis Is plaquenil a mitochondrial toxin Plaquenil and citalopram qt prolongation Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Higher doses of medications that weaken your immune system are more likely to increase your risk of getting a fungal infection. 5,11,13,14. Click on the sections below to see lists of corticosteroids and TNF inhibitors that can increase the chances of getting a fungal infection. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Does hydroxychloroquine tabs disrupt immune system Hydroxychloroquine Side-effects, uses, time to work, Medications that Weaken Your Immune System and Fungal. Chloroquine induces degradationPlaquenil macular changesWhat will happen if i don't take plaquenilCan plaquenil cause loss of hearing It alters your immune system, but as far as I know, it doesn't actually suppress it. Plus, if you have only been on it a month, it's probably not built up enough in your body to have much of an effect. I have actually been way HEALTHIER than ever since being on Plaquenil AND Methotrexate, which DOES suppress the immune system - go figure! Does Plaquenil supress the immune system?. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hi everyone. Just wondered if anyone can tell me whether hydroxy suppresses the immune system. And if so, to what extent. I know it's not as harsh as some of the other drugs but just wondered what people's experiences are. The immune system can be divided into two components the innate born with immune system and adaptive develop through life immune system. The innate component is the first line of defense. It reacts very quickly to fight off things that are foreign to the body such as viruses and bacteria and identifying damaged cells. How does Plaquenil work? Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. How do you take Plaquenil? You take Plaquenil as a pill 1 or 2 times a day. Take the pills with food or milk.